Publications

Full list of publications: http://bit.ly/2oqL0P9

Alterations to the Cardiac Metabolome Induced by Chronic T. cruzi Infection Relate to the Degree of Cardiac Pathology. Hoffman K, Liu Z, Hossain E, Bottazzi ME, Hotez PJ, Jones KM, McCall LI. ACS Infect Dis. 2021 Apr 12. doi: 10.1021/acsinfecdis.0c00816. Online ahead of print. PMID: 33843195

Quo vadis? Central Rules of Pathogen and Disease Tropism. McCall LI. Front Cell Infect Microbiol. 2021 Feb 25;11:640987. doi: 10.3389/fcimb.2021.640987. eCollection 2021. PMID: 33718287

Tryp-ing Up Metabolism: Role of Metabolic Adaptations in Kinetoplastid Disease Pathogenesis. Parab AR, McCall LI. Infect Immun. 2021 Mar 17;89(4):e00644-20. doi: 10.1128/IAI.00644-20. Print 2021 Mar 17. PMID: 33526564

Feature-based molecular networking in the GNPS analysis environment. Nothias LF, Petras D, Schmid R, Dührkop K, Rainer J, Sarvepalli A, Protsyuk I, Ernst M, Tsugawa H, Fleischauer M, Aicheler F, Aksenov AA, Alka O, Allard PM, Barsch A, Cachet X, Caraballo-Rodriguez AM, Da Silva RR, Dang T, Garg N, Gauglitz JM, Gurevich A, Isaac G, Jarmusch AK, Kameník Z, Kang KB, Kessler N, Koester I, Korf A, Le Gouellec A, Ludwig M, Martin H C, McCall LI, McSayles J, Meyer SW, Mohimani H, Morsy M, Moyne O, Neumann S, Neuweger H, Nguyen NH, Nothias-Esposito M, Paolini J, Phelan VV, Pluskal T, Quinn RA, Rogers S, Shrestha B, Tripathi A, van der Hooft JJJ, Vargas F, Weldon KC, Witting M, Yang H, Zhang Z, Zubeil F, Kohlbacher O, Böcker S, Alexandrov T, Bandeira N, Wang M, Dorrestein PC. Nat Methods. 2020 Sep;17(9):905-908. doi: 10.1038/s41592-020-0933-6. Epub 2020 Aug 24. PMID: 32839597

ReDU: a framework to find and reanalyze public mass spectrometry data. Jarmusch AK, Wang M, Aceves CM, Advani RS, Aguirre S, Aksenov AA, Aleti G, Aron AT, Bauermeister A, Bolleddu S, Bouslimani A, Caraballo Rodriguez AM, Chaar R, Coras R, Elijah EO, Ernst M, Gauglitz JM, Gentry EC, Husband M, Jarmusch SA, Jones KL 2nd, Kamenik Z, Le Gouellec A, Lu A, McCall LI, McPhail KL, Meehan MJ, Melnik AV, Menezes RC, Montoya Giraldo YA, Nguyen NH, Nothias LF, Nothias-Esposito M, Panitchpakdi M, Petras D, Quinn RA, Sikora N, van der Hooft JJJ, Vargas F, Vrbanac A, Weldon KC, Knight R, Bandeira N, Dorrestein PC. Nat Methods. 2020 Sep;17(9):901-904. doi: 10.1038/s41592-020-0916-7. Epub 2020 Aug 17. PMID: 32807955

Mapping of host-parasite-microbiome interactions reveals metabolic determinants of tropism and tolerance in Chagas disease. Hossain E, Khanam S, Dean DA, Wu C, Lostracco-Johnson S, Thomas D, Kane SS, Parab AR, Flores K, Katemauswa M, Gosmanov C, Hayes SE, Zhang Y, Li D, Woelfel-Monsivais C, Sankaranarayanan K, McCall LI. Sci Adv. 2020 Jul 22;6(30):eaaz2015. doi: 10.1126/sciadv.aaz2015. eCollection 2020 Jul. PMID: 32766448

Insights gained into respiratory infection pathogenesis using lung tissue metabolomics. Bernatchez JA, McCall LI. PLoS Pathog. 2020 Jul 14;16(7):e1008662. doi: 10.1371/journal.ppat.1008662. eCollection 2020 Jul. PMID: 32663224

Scaffold and Parasite Hopping: Discovery of New Protozoal Proliferation Inhibitors. Singh B, Bernatchez JA, McCall LI, Calvet CM, Ackermann J, Souza JM, Thomas D, Silva EM, Bachovchin KA, Klug DM, Jalani HB, Bag S, Buskes MJ, Leed SE, Roncal NE, Penn EC, Erath J, Rodriguez A, Sciotti RJ, Campbell RF, McKerrow J, Siqueira-Neto JL, Ferrins L, Pollastri MP. ACS Med Chem Lett. 2020 Jan 10;11(3):249-257. doi: 10.1021/acsmedchemlett.9b00453. eCollection 2020 Mar 12. PMID: 32184953

Local Phenomena Shape Backyard Soil Metabolite Composition. Nguyen TD, Lesani M, Forrest I, Lan Y, Dean DA, Gibaut QMR, Guo Y, Hossain E, Olvera M, Panlilio H, Parab AR, Wu C, Bernatchez JA, Cichewicz RH, McCall LI. Metabolites. 2020 Feb 29;10(3):86. doi: 10.3390/metabo10030086. PMID: 32121389

Home chemical and microbial transitions across urbanization. McCall LI, Callewaert C, Zhu Q, Song SJ, Bouslimani A, Minich JJ, Ernst M, Ruiz-Calderon JF, Cavallin H, Pereira HS, Novoselac A, Hernandez J, Rios R, Branch OH, Blaser MJ, Paulino LC, Dorrestein PC, Knight R, Dominguez-Bello MG. Nat Microbiol. 2019 Nov 4. doi: 10.1038/s41564-019-0593-4. PMID: 31686026

Ethical priority of the most actionable system of biomolecules: the metabolome. Lewis CM Jr, McCall LI, Sharp RR, Spicer PG. Am J Phys Anthropol. 2019 Oct 23. doi: 10.1002/ajpa.23943.  PMID: 31643083

Design of Gallinamide A Analogs as Potent Inhibitors of the Cysteine Proteases Human Cathepsin L and Trypanosoma cruzi Cruzain. Boudreau PD, Miller BW, McCall LI, Almaliti J, Reher R, Hirata K, Le T, Siqueira-Neto JL, Hook V, Gerwick WH. J Med Chem. 2019 Oct 24;62(20):9026-9044. doi: 10.1021/acs.jmedchem.9b00294. PMID: 31539239

A complete Leishmania donovani reference genome identifies novel genetic variations associated with virulence. Lypaczewski P, Hoshizaki J, Zhang WW, McCall LI, Torcivia-Rodriguez J, Simonyan V, Kaur A, Dewar K, Matlashewski G. Sci Rep. 2018 Nov 8;8(1):16549. doi: 10.1038/s41598-018-34812-x. PMID: 30409989

Cysteine proteases in protozoan parasites. Siqueira-Neto JL, Debnath A, McCall LI, Bernatchez JA, Ndao M, Reed SL, Rosenthal PJ. PLoS Negl Trop Dis. 2018 Aug 23;12(8):e0006512. doi: 10.1371/journal.pntd.0006512. PMID: 30138453

Best practices for analysing microbiomes. Knight R, Vrbanac A, Taylor BC, Aksenov A, Callewaert C, Debelius J, Gonzalez A, Kosciolek T, McCall LI, McDonald D, Melnik AV, Morton JT, Navas J, Quinn RA, Sanders JG, Swafford AD, Thompson LR, Tripathi A, Xu ZZ, Zaneveld JR, Zhu Q, Caporaso JG, Dorrestein PC. Nat Rev Microbiol. 2018 Jul;16(7):410-422. doi: 10.1038/s41579-018-0029-9. PMID: 29795328

Metabolomics: Eavesdropping on silent conversations between hosts and their unwelcome guests. Newsom SN, McCall LI. PLoS Pathog. 2018 Apr 5;14(4):e1006926. doi: 10.1371/journal.ppat.1006926. PMID: 29621358

Experimental Chagas disease-induced perturbations of the fecal microbiome and metabolome. McCall LI, Tripathi A, Vargas F, Knight R, Dorrestein PC, Siqueira-Neto JL. PLoS Negl Trop Dis. 2018 Mar 12;12(3):e0006344. doi: 10.1371/journal.pntd.0006344. PMID: 29529084

Mass Spectrometry-Based Chemical Cartography of a Cardiac Parasitic Infection. McCall LI, Morton JT, Bernatchez JA, de Siqueira-Neto JL, Knight R, Dorrestein PC, McKerrow JH. Anal Chem. 2017 Oct 3;89(19):10414-10421. doi: 10.1021/acs.analchem.7b02423. Epub 2017 Sep 22. PMID: 28892370

Rapid Chagas Disease Drug Target Discovery Using Directed Evolution in Drug-Sensitive Yeast. Ottilie S, Goldgof GM, Calvet CM, Jennings GK, LaMonte G, Schenken J, Vigil E, Kumar P, McCall LI, Lopes ES, Gunawan F, Yang J, Suzuki Y, Siqueira-Neto JL, McKerrow JH, Amaro RE, Podust LM, Durrant JD, Winzeler EA. ACS Chem Biol. 2017 Feb 17;12(2):422-434. doi: 10.1021/acschembio.6b01037. Epub 2016 Dec 23. PMID: 27977118

Mass Spectrometry-Based Visualization of Molecules Associated with Human Habitats.  Petras D, Nothias LF, Quinn RA, Alexandrov T, Bandeira N, Bouslimani A, Castro-Falcón G, Chen L, Dang T, Floros DJ, Hook V, Garg N, Hoffner N, Jiang Y, Kapono CA, Koester I, Knight R, Leber CA, Ling TJ, Luzzatto-Knaan T, McCall LI, McGrath AP, Meehan MJ, Merritt JK, Mills RH, Morton J, Podvin S, Protsyuk I, Purdy T, Satterfield K, Searles S, Shah S, Shires S, Steffen D, White M, Todoric J, Tuttle R, Wojnicz A, Sapp V, Vargas F, Yang J, Zhang C, Dorrestein PC. Anal Chem. 2016 Nov 15;88(22):10775-10784. Epub 2016 Oct 24. PMID: 27732780

Location, Location, Location: Five Facts about Tissue Tropism and Pathogenesis. McCall LI, Siqueira-Neto JL, McKerrow JH. PLoS Pathog. 2016 May 26;12(5):e1005519. doi: 10.1371/journal.ppat.1005519. eCollection 2016 May. PMID: 27227827

Machine Learning Models and Pathway Genome Data Base for Trypanosoma cruzi Drug Discovery. Ekins S, de Siqueira-Neto JL, McCall LI, Sarker M, Yadav M, Ponder EL, Kallel EA, Kellar D, Chen S, Arkin M, Bunin BA, McKerrow JH, Talcott C. PLoS Negl Trop Dis. 2015 Jun 26;9(6):e0003878. doi: 10.1371/journal.pntd.0003878. eCollection 2015. PMID: 26114876

Adaptation of Leishmania donovani to cutaneous and visceral environments: in vivo selection and proteomic analysis.  McCall LI, Zhang WW, Dejgaard K, Atayde VD, Mazur A, Ranasinghe S, Liu J, Olivier M, Nilsson T, Matlashewski G. J Proteome Res. 2015 Feb 6;14(2):1033-59. doi: 10.1021/pr5010604. Epub 2015 Jan 13. PMID: 25536015